Details of the Drug

General Information of Drug (ID: DMKVIS5)

Drug Name

RG7907

Synonyms

CPAM

Indication

Disease Entry	ICD 11	Status	REF
Hepatitis B	1E51	Phase 1	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

352.15

Logarithm of the Partition Coefficient (xlogp)

3.1

Rotatable Bond Count (rotbonds)

3

Hydrogen Bond Donor Count (hbonddonor)

3

Hydrogen Bond Acceptor Count (hbondacc)

4

Chemical Identifiers

Formula: C15H11BrFNO3
IUPAC Name: (E)-N-(2-bromo-4-fluorophenyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide
Canonical SMILES: C1=CC(=C(C=C1/C=C/C(=O)NC2=C(C=C(C=C2)F)Br)O)O
InChI: InChI=1S/C15H11BrFNO3/c16-11-8-10(17)3-4-12(11)18-15(21)6-2-9-1-5-13(19)14(20)7-9/h1-8,19-20H,(H,18,21)/b6-2+
InChIKey: XOHNWHLPLQQICZ-QHHAFSJGSA-N

Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Hepatitis B virus Capsid protein (HBV C)	TTM42UJ	CAPSD_HBVD3	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Clinical pipeline report, company report or official report of Roche.