General Information of Drug (ID: DMLI9U6)

Drug Name
AVI-7537
Indication
Disease Entry ICD 11 Status REF
Ebola virus infection 1D60.0 Phase 1 [1]
Drug Type
Antisense drug
Sequence
GCCATGGTTTTTTCTCAGG
Cross-matching ID
DrugBank ID
DB15433
TTD ID
D09ELC

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Ebola virus VP24 messenger RNA (EV VP24 mRNA) TTDJLWQ VP24_EBOSU Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01593072) A Study to Assess the Safety, Tolerability and Pharmacokinetics of AVI-7537 in Healthy Adult Volunteers. U.S. National Institutes of Health.
2 Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus Infections. Viruses. 2012 November; 4(11): 2806-2830.