Details of the Drug | DrugMAP

General Information of Drug (ID: DMLVY7A)

Drug Name	Imidazo triazine derivative 1
Synonyms	PMID27321640-Compound-64
Drug Type	Small molecular drug
Structure
Structure	3D MOL			2D MOL
#Ro5 Violations (Lipinski): 0	Molecular Weight (mw)			401.4
	Logarithm of the Partition Coefficient (xlogp)			3.1
	Rotatable Bond Count (rotbonds)			3
	Hydrogen Bond Donor Count (hbonddonor)			0
	Hydrogen Bond Acceptor Count (hbondacc)			8
Chemical Identifiers	Formula C19H18F3N7 IUPAC Name N,N,7-trimethyl-5-[1-methyl-5-[4-(trifluoromethyl)phenyl]pyrazol-4-yl]imidazo[5,1-f][1,2,4]triazin-4-amine Canonical SMILES CC1=NC(=C2N1N=CN=C2N(C)C)C3=C(N(N=C3)C)C4=CC=C(C=C4)C(F)(F)F InChI InChI=1S/C19H18F3N7/c1-11-26-15(17-18(27(2)3)23-10-25-29(11)17)14-9-24-28(4)16(14)12-5-7-13(8-6-12)19(20,21)22/h5-10H,1-4H3 InChIKey UXZUQMRCSXERSI-UHFFFAOYSA-N
Cross-matching ID	PubChem CID 68182028 TTD ID D00ONN

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Phosphodiesterase 2A (PDE2A)	TTJGW1Z	PDE2A_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

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References

1	Towards selective phosphodiesterase 2A (PDE2A) inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2016 Aug;26(8):933-46.