Details of the Drug

General Information of Drug (ID: DMMKE2H)

Drug Name
Valoctocogene roxaparvovec
Synonyms BMN 270
Indication
Disease Entry ICD 11 Status REF
Haemophilia A 3B10.0 Phase 3 [1]
Drug Type
Gene therapy
Cross-matching ID
DrugBank ID
DB15561
TTD ID
D7HLI1

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Coagulation factor VIII (F8) TT1290U FA8_HUMAN Replacement [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Haemophilia A
ICD Disease Classification 3B10.0
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Coagulation factor VIII (F8) DTT F8 1.08E-22 0.89 1.82
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04323098) Study to Evaluate the Efficacy and Safety of Valoctocogene Roxaparvovec, With Prophylactic Steroids in Hemophilia A (GENEr8-3). U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of BioMarin Pharmaceutical.