Details of the Drug

General Information of Drug (ID: DMN5YUK)

• Drug Name: Sulfonamide derivative 7
• Synonyms: PMID29473428-Compound-78
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 300.3
  Logarithm of the Partition Coefficient (xlogp); 2.9
  Rotatable Bond Count (rotbonds); 4
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 5
• Chemical Identifiers:
  Formula: C15H12N2O3S
  IUPAC Name: N-(4-phenyl-1,2-oxazol-5-yl)benzenesulfonamide
  Canonical SMILES: C1=CC=C(C=C1)C2=C(ON=C2)NS(=O)(=O)C3=CC=CC=C3
  InChI: InChI=1S/C15H12N2O3S/c18-21(19,13-9-5-2-6-10-13)17-15-14(11-16-20-15)12-7-3-1-4-8-12/h1-11,17H
  InChIKey: KJPWMAIBFGUKIA-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 110402129
  TTD ID: D0R8OW

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Indoleamine 2,3-dioxygenase 1 (IDO1)	TTZJYKH	I23O1_HUMAN	Inhibitor	[1]

References

• [1] A patent review of IDO1 inhibitors for cancer.Expert Opin Ther Pat. 2018 Apr;28(4):317-330.