Details of the Drug

General Information of Drug (ID: DMNX5VI)

• Drug Name: D-fructose
• Synonyms: D-Arabino-Hex-2-ulo-Pyranose; D-Fructopyranose; D-Fructopyranoside; D-Fructose; D-arabino-Hex-2-ulopyranose; Fructopyranose; Fructopyranoside; Fructose; LKDRXBCSQODPBY-VRPWFDPXSA-N; Q27117234; SCHEMBL239448; AKOS004910390; C05003; CHEBI:37714; CHEMBL2325229; CTK2F9011; D-Fru; EB37038E-44A6-4AF7-B0D8-47A315AD2F74; F0317; Fru; [14C]-Fructose
• #Ro5 Violations (Lipinski): 1:
  Molecular Weight (mw); 180.16
  Logarithm of the Partition Coefficient (xlogp); -2.8
  Rotatable Bond Count (rotbonds); 1
  Hydrogen Bond Donor Count (hbonddonor); 5
  Hydrogen Bond Acceptor Count (hbondacc); 6
• Chemical Identifiers:
  Formula: C6H12O6
  IUPAC Name: (3S,4R,5R)-2-(hydroxymethyl)oxane-2,3,4,5-tetrol
  Canonical SMILES: C1C(C(C(C(O1)(CO)O)O)O)O
  InChI: LKDRXBCSQODPBY-VRPWFDPXSA-N
  InChIKey: 1S/C6H12O6/c7-2-6(11)5(10)4(9)3(8)1-12-6/h3-5,7-11H,1-2H2/t3-,4-,5+,6?/m1/s1
• Cross-matching ID:
  PubChem CID: 2723872
  ChEBI ID: CHEBI:37714
  CAS Number: 7660-25-5
  UNII: 0LJG9X2ZUL
  DrugBank ID: DB02561
  INTEDE ID: DR2156

Molecular Interaction Atlas of This Drug

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
D-psicose 3-epimerase (DPEase) Main DME	DEA2SU9	DPES_RUMCH	Substrate	[1], [2]

References

• [1] Highly efficient production of Clostridium cellulolyticum H10 D-psicose 3-epimerase in Bacillus subtilis and use of these cells to produce D-psicose. Microb Cell Fact. 2018 Nov 28;17(1):188.
• [2] Anaerobic bacteria as producers of antibiotics. Appl Microbiol Biotechnol. 2012 Oct;96(1):61-7.