General Information of Drug (ID: DMO3QAZ)

Drug Name
DNL310
Indication
Disease Entry ICD 11 Status REF
Mucopolysaccharidosis II 5C56.31 Phase 2/3 [1]
Drug Type
Enzyme replacement
Cross-matching ID
TTD ID
DTV58L

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Iduronate 2-sulfatase (IDS) TTNY2AP IDS_HUMAN Replacement [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT05371613) A Phase 2/3, Multicenter, Double-Blind, Randomized Study to Determine the Efficacy and Safety of DNL310 vs Idursulfase in Pediatric Participants With Neuronopathic or Non-Neuronopathic Mucopolysaccharidosis Type II. U.S.National Institutes of Health.
2 Clinical pipeline report, company report or official report of Denali