Details of the Drug

General Information of Drug (ID: DMOG1LX)

Drug Name
IGN-101
Synonyms Cancer vaccine, Igeneon; Anti-EpCam murine monoclonal antibody 17-A carcinoma vaccine; Aluminum-adsorbed murine monoclonal antibody 17-1A (edrecolomab) vaccine antigen (cancer), Igeneon
Indication
Disease Entry ICD 11 Status REF
Colorectal cancer 2B91.Z Discontinued in Phase 2 [1]
Drug Type
Vaccine
Cross-matching ID
TTD ID
D0J9KC

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tumor-associated calcium signal transducer 1 (EPCAM) TTZ8WH4 EPCAM_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Colorectal cancer
ICD Disease Classification 2B91.Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tumor-associated calcium signal transducer 1 (EPCAM) DTT EPCAM 5.99E-02 -0.11 -1.11
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013809)
2 Drug evaluation: IGN-101--an anti-EpCAM murine antibody vaccine for cancer. Curr Opin Mol Ther. 2006 Aug;8(4):358-65.