Details of the Drug

General Information of Drug (ID: DMOOK7D)

Drug Name

LB42708

Synonyms

LB42708; 226929-39-1; LB 42708; C30H27BrN4O2; SCHEMBL6975755; GTPL8029; AOB5942; MolPort-023-277-136; HMS3653F07; BCP09683; ZINC1490366; EX-A2090; s7467; 2507AH; AKOS024458079; SB19586; NCGC00370772-05; LB-42708; BC600547; SW220047-1; FT-0720438; 4-[[1-[[1-[(4-Bromophenyl)methyl]-1H-imidazol-5-yl]methyl]-4-(1-naphthalenyl)-1H-pyrrol-3-yl]carbonyl]morpholine; 4-[1-({1-[(4-bromophenyl)methyl]-1H-imidazol-5-yl}methyl)-4-(naphthalen-1-yl)-1H-pyrrole-3-carbonyl]morpholine

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

Chemical Identifiers

Formula: C30H27BrN4O2
Canonical SMILES: C1COCCN1C(=O)C2=CN(C=C2C3=CC=CC4=CC=CC=C43)CC5=CN=CN5CC6=CC=C(C=C6)Br
InChI: 1S/C30H27BrN4O2/c31-24-10-8-22(9-11-24)17-35-21-32-16-25(35)18-33-19-28(27-7-3-5-23-4-1-2-6-26(23)27)29(20-33)30(36)34-12-14-37-15-13-34/h1-11,16,19-21H,12-15,17-18H2
InChIKey: GUUIRIMAQGOLHT-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 10099206
TTD ID: D02KVR

References

1	The farnesyltransferase inhibitor LB42708 suppresses vascular endothelial growth factor-induced angiogenesis by inhibiting ras-dependent mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signal pathways. Mol Pharmacol. 2010 Jul;78(1):142-50.