Details of the Drug

General Information of Drug (ID: DMOUTNA)

• Drug Name: Methionine Phosphonate
• Synonyms: METHIONINE PHOSPHONATE; (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHONIC ACID; 1pfu; AC1L9GS3; SCHEMBL4321583; DB02151; [(R)-1-Amino-3-(methylthio)propyl]phosphonic acid; [(1R)-1-amino-3-methylsulfanylpropyl]phosphonic acid; [(1R)-1-amino-3-(methylsulfanyl)propyl]phosphonic acid

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 1:
  Molecular Weight (mw); 185.18
  Logarithm of the Partition Coefficient (xlogp); -3.7
  Rotatable Bond Count (rotbonds); 4
  Hydrogen Bond Donor Count (hbonddonor); 3
  Hydrogen Bond Acceptor Count (hbondacc); 5
• Chemical Identifiers:
  Formula: C4H12NO3PS
  IUPAC Name: [(1R)-1-amino-3-methylsulfanylpropyl]phosphonic acid
  Canonical SMILES: CSCC[C@H](N)P(=O)(O)O
  InChI: InChI=1S/C4H12NO3PS/c1-10-3-2-4(5)9(6,7)8/h4H,2-3,5H2,1H3,(H2,6,7,8)/t4-/m1/s1
  InChIKey: XKCSXHUCPYVQIW-SCSAIBSYSA-N
• Cross-matching ID:
  PubChem CID: 444719
  DrugBank ID: DB02151
  TTD ID: D0Z2KB

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Streptococcus Methionyl-tRNA synthetase (Stre-coc metG)	TTOJ46K	SYM_STRP1	Inhibitor	[1]

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.