Details of the Drug

General Information of Drug (ID: DMOX7FJ)

• Drug Name: ISIS 7453

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Antisense drug
• Sequence: TACGCCAACAGCTCC
• Cross-matching ID: TTD ID: D0A4MW

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
KRAS messenger RNA (KRAS mRNA)	TTM8FR7	RASK_HUMAN	Not Available	[1]

References

• [1] US patent application no. 5,965,722, Antisense inhibition of ras gene with chimeric and alternating oligonucleotides.