Details of the Drug

General Information of Drug (ID: DMOXIZC)

• Drug Name: Sulfonamide derivative 8
• Synonyms: PMID29473428-Compound-79
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 280.34
  Logarithm of the Partition Coefficient (xlogp); 2.3
  Rotatable Bond Count (rotbonds); 5
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 5
• Chemical Identifiers:
  Formula: C13H16N2O3S
  IUPAC Name: 2-methyl-N-(5-phenyl-1,2-oxazol-4-yl)propane-1-sulfonamide
  Canonical SMILES: CC(C)CS(=O)(=O)NC1=C(ON=C1)C2=CC=CC=C2
  InChI: InChI=1S/C13H16N2O3S/c1-10(2)9-19(16,17)15-12-8-14-18-13(12)11-6-4-3-5-7-11/h3-8,10,15H,9H2,1-2H3
  InChIKey: PNZONOIXJUOMIU-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 118895401
  TTD ID: D06FHJ

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Indoleamine 2,3-dioxygenase 1 (IDO1)	TTZJYKH	I23O1_HUMAN	Inhibitor	[1]

References

• [1] A patent review of IDO1 inhibitors for cancer.Expert Opin Ther Pat. 2018 Apr;28(4):317-330.