Details of the Drug

General Information of Drug (ID: DMOZ84C)

• Drug Name: US10077269, Example 6
• Synonyms: SCHEMBL17492361; US10077269, Example 6; KZFDLYSKEWBCTB-UHFFFAOYSA-N; BDBM285533; N-Cyclopropyl-3-([1,2,4]triazolo[1,5-a]pyridin-6-yl)imidazo[1,2-b]pyridazine-2-carboxamide (6); N-Cyclopropyl-3-([1,2,4]triazolo[1,5-a]pyridin-6-yl )imidazo[1,2-b]pyridazine-2-carboxamide
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 319.32
  Logarithm of the Partition Coefficient (xlogp); 1
  Rotatable Bond Count (rotbonds); 3
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 5
• Chemical Identifiers:
  Formula: C16H13N7O
  IUPAC Name: N-cyclopropyl-3-([1,2,4]triazolo[1,5-a]pyridin-6-yl)imidazo[1,2-b]pyridazine-2-carboxamide
  Canonical SMILES: C1CC1NC(=O)C2=C(N3C(=N2)C=CC=N3)C4=CN5C(=NC=N5)C=C4
  InChI: InChI=1S/C16H13N7O/c24-16(20-11-4-5-11)14-15(23-13(21-14)2-1-7-18-23)10-3-6-12-17-9-19-22(12)8-10/h1-3,6-9,11H,4-5H2,(H,20,24)
  InChIKey: KZFDLYSKEWBCTB-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 118863057
  TTD ID: D05TQB

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Phosphodiesterase 4C (PDE4C)	TT6A59G	PDE4C_HUMAN	Inhibitor	[1]

References

• [1] Imidazopyridazine compounds. US9598421.