Details of the Drug

General Information of Drug (ID: DMPY8D3)

Drug Name

4-Amino-3-hydroxy-butyric acid

Synonyms

4-Amino-3-hydroxybutanoic acid; 924-49-2; 4-Amino-3-hydroxybutyric acid; Gabob; DL-4-Amino-3-hydroxybutyric acid; 3-Hydroxy-GABA; Gamibetal; Gabomade; Gaboril; Idramina; Gaminal; Buksamin; Gabimex; Bogil; 352-21-6; Gamma-amino-beta-hydroxybutyric acid; Butanoic acid, 4-amino-3-hydroxy-; Buxamine; Buxamin; Gabobe; beta-Oxy-gaba; 3-Hydroxy-4-aminobutyric acid; Buxamine (VAN); NSC 40244; gamma-Amino-beta-hydroxybutyrate; beta-Hydroxy-gamma-aminobutyrate; 4-Amino-3-hydroxy-butyric acid; BUTYRIC ACID, 4-AMINO-3-HYDROXY-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 1

Molecular Weight (mw)

119.12

Logarithm of the Partition Coefficient (xlogp)

-4.1

Rotatable Bond Count (rotbonds)

3

Hydrogen Bond Donor Count (hbonddonor)

3

Hydrogen Bond Acceptor Count (hbondacc)

4

Chemical Identifiers

Formula: C4H9NO3
IUPAC Name: 4-amino-3-hydroxybutanoic acid
Canonical SMILES: C(C(CN)O)C(=O)O
InChI: InChI=1S/C4H9NO3/c5-2-3(6)1-4(7)8/h3,6H,1-2,5H2,(H,7,8)
InChIKey: YQGDEPYYFWUPGO-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 2149
ChEBI ID: CHEBI:16080
CAS Number: 924-49-2
TTD ID: D00PUF

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Gamma-aminobutyric acid receptor (GAR)	TTNJYV2	NOUNIPROTAC	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	GABA agonists. Resolution, absolute stereochemistry, and enantioselectivity of (S)-(+)- and (R)-(-)-dihydromuscimol. J Med Chem. 1985 Nov;28(11):1612-7.