Details of the Drug

General Information of Drug (ID: DMQMXIO)

Drug Name

LEURUBICIN

Synonyms

Doxogenix L; CT-012002; L-ADR; LEU-DOX; RP-39937; Leurubicin; N-L-Leucyladriamycin; N-L-Leucyldoxorubicin; E-88/032 (hydrochloride); (8S,10S)-10-[[3-[(S)-2-Amino-4-methylvaleramido]-2,3,6-trideoxy-alphal-L-lyxo-hexopyranosyl]oxy]-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; (8S-cis)-6,8,11-Trihydroxy-8-(hydroxyacetyl)-10-[2,3,6-trideoxy-3-(L-leucylamino)-alpha-L-lyxohexopyranosyloxy]-1-methoxy-5,8,9,10,12-hexahydronaphthacene-5,12-dione

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Approved	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C33H40N2O12
Canonical SMILES: CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)NC(=O)C(CC(C)C)N)O
InChI: 1S/C33H40N2O12/c1-13(2)8-17(34)32(43)35-18-9-22(46-14(3)27(18)38)47-20-11-33(44,21(37)12-36)10-16-24(20)31(42)26-25(29(16)40)28(39)15-6-5-7-19(45-4)23(15)30(26)41/h5-7,13-14,17-18,20,22,27,36,38,40,42,44H,8-12,34H2,1-4H3,(H,35,43)/t14-,17-,18-,20-,22-,27+,33-/m0/s1
InChIKey: HROXIDVVXKDCBD-ZUWKMVCBSA-N

Cross-matching ID

PubChem CID: 68897
CAS Number: 70774-25-3
TTD ID: D0T5XN

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001292)