Details of the Drug

General Information of Drug (ID: DMQSGM0)

Drug Name

Hydroxyamphetamine Hydrobromide

Synonyms

Paredrine; 4-hydroxyamphetamine

Indication

Disease Entry	ICD 11	Status	REF
Horner syndrome	8D8A.1	Approved	[1]
Mydriasis	LA11.62	Approved	[2]
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Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

#Ro5 Violations (Lipinski):
0

Molecular Weight

232.12

Logarithm of the Partition Coefficient

Not Available

Rotatable Bond Count

2

Hydrogen Bond Donor Count

3

Hydrogen Bond Acceptor Count

2

Chemical Identifiers

Formula: C9H14BrNO
IUPAC Name: 4-(2-aminopropyl)phenol;hydrobromide
Canonical SMILES: CC(CC1=CC=C(C=C1)O)N.Br
InChI: InChI=1S/C9H13NO.BrH/c1-7(10)6-8-2-4-9(11)5-3-8;/h2-5,7,11H,6,10H2,1H3;1H
InChIKey: RZCJLMTXBMNRAD-UHFFFAOYSA-N

Cross-matching ID

Repurposed Drugs (RPD)

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Trace amine-associated receptor-1 (TAAR1)	TTIU98M	TAAR1_HUMAN	Modulator	[3]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Horner syndrome

ICD Disease Classification

8D8A.1

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Trace amine-associated receptor-1 (TAAR1)	DTT	TAAR1	6.12E-01	-0.01	-0.06

Molecular Expression Atlas (MEA)

Jump to Detail Molecular Expression Atlas of This Drug

References

1	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2	Hydroxyamphetamine Hydrobromide FDA Label
3	Diagnostic pharmacology of the pupil.Clin Neuropharmacol.1985;8(1):27-37.