Details of the Drug

General Information of Drug (ID: DMRGTZ2)

Drug Name

SSTarbaclofen

Indication

Disease Entry	ICD 11	Status	REF
Autism spectrum disorder	6A02	Phase 2	[1]
Fragile X syndrome	LD55	Phase 2	[1]
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Cross-matching ID

Repurposed Drugs (RPD)

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Gamma-aminobutyric acid B receptor (GABBR)	TTDCVZW	GABR1_HUMAN ; GABR2_HUMAN	Modulator	[2]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	ClinicalTrials.gov (NCT01288716) Study of Arbaclofen for the Treatment of Social Withdrawal in Subjects With Autism Spectrum Disorders. U.S. National Institutes of Health.
2	Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen. Sci Transl Med. 2012 Sep 19;4(152):152ra128.