Details of the Drug

General Information of Drug (ID: DMRJ1HC)

Drug Name

Liposomal amikacin

Synonyms

AriKayce; Liposomal Amikacin; AC1L9V75; SMP1_000015; Amikacin containing Liposome consisting of Soy Phosphatidylcholine(SPC) and Phosphatidylglycerol(PG); 4-amino-N-[(1R,2S,3S,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxy-tetrahydropyran-2-yl]oxy-3-hydroxy-cyclohexyl]-2-hydroxy-butanamide; 4-amino-N-[(1R,2S,3S,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(amin

Indication

Disease Entry	ICD 11	Status	REF
Mycobacterium infection	1B10-1B21	Phase 3	[1]
Bronchiectasis	CA24	Phase 2	[1]
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Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C22H43N5O13
Canonical SMILES: C1C(C(C(C(C1NC(=O)C(CCN)O)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(C(C(C(O3)CN)O)O)O)N
InChI: 1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/t6-,7+,8?,9+,10+,11-,12+,13+,14+,15-,16+,17-,18?,19-,21+,22+/m0/s1
InChIKey: LKCWBDHBTVXHDL-CAIQVSFASA-N

Cross-matching ID

PubChem CID: 456591
TTD ID: D0X4UP

Repurposed Drugs (RPD)

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References

1	Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)