Details of the Drug

General Information of Drug (ID: DMRKO49)

Drug Name
Ribose-5-Phosphate
Synonyms
ribose-5-phosphate; Ribose phosphate; Ribose 5-monophosphate; 5-O-phosphono-D-ribose; D-ribose-5-phosphoric acid; D-Ribose 5-(dihydrogen phosphate); 4300-28-1; R-5-P; UNII-4B2428FLTO; Ribose, 5-(dihydrogen phosphate), D-; D-ribose-5-phosphate; 4B2428FLTO; aldehydo-D-ribose 5-phosphate; [(2R,3R,4R)-2,3,4-trihydroxy-5-oxopentyl] dihydrogen phosphate; R52; EINECS 224-310-2; AC1Q6RUZ; bmse000278; AC1L2U8E; D-Ribose 5-phosphoric acid; SCHEMBL21609; 3615-55-2; CTK1D6888; CHEBI:17797; Ribose, 5-(dihydrogen phosphate)
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 230.11
Logarithm of the Partition Coefficient (xlogp) -3.4
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 5
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C5H11O8P
IUPAC Name
[(2R,3R,4R)-2,3,4-trihydroxy-5-oxopentyl] dihydrogen phosphate
Canonical SMILES
C([C@H]([C@H]([C@H](C=O)O)O)O)OP(=O)(O)O
InChI
InChI=1S/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h1,3-5,7-9H,2H2,(H2,10,11,12)/t3-,4+,5-/m0/s1
InChIKey
PPQRONHOSHZGFQ-LMVFSUKVSA-N
Cross-matching ID
PubChem CID
77982
ChEBI ID
CHEBI:17797
CAS Number
4300-28-1
DrugBank ID
DB02053
TTD ID
D02KLU

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bacterial Deoxy-D-manno-octulosonate 8-phosphate synthase (Bact kdsA) TTVNA43 KDSA_ECOLI Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.