General Information of Drug (ID: DMS20X6)

Drug Name
CDX-1135
Synonyms SCR1; BRL-55730; Soluble complement receptor type 1, AVANT; Soluble complement receptor type 1, Celldex; YM-203; TP-10, AVANT Immunotherapeutics; TP-10, Celldex
Indication
Disease Entry ICD 11 Status REF
Macular degeneration 9B78.3 Phase 1 [1]
Cross-matching ID
TTD ID
D0T4NV

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Complement receptor type 1 (CR1) TTEA8OW CR1_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01791686) Clinical Trial of CDX-1135 in Pediatric and Adult Patients With Dense Deposit Disease. U.S. National Institutes of Health.
2 Complement activation is critical for placental ischemia-induced hypertension in the rat. Mol Immunol. 2013 Nov;56(1-2):91-7.