Details of the Drug | DrugMAP

General Information of Drug (ID: DMS415A)

Drug Name	US10149841, Compound 9
Synonyms	SCHEMBL19808943; US10149841, Compound 9; BDBM306798
Drug Type	Small molecular drug
Structure
Structure	3D MOL			2D MOL
#Ro5 Violations (Lipinski): 0	Molecular Weight (mw)			324.24
	Logarithm of the Partition Coefficient (xlogp)			2
	Rotatable Bond Count (rotbonds)			5
	Hydrogen Bond Donor Count (hbonddonor)			3
	Hydrogen Bond Acceptor Count (hbondacc)			8
Chemical Identifiers	Formula C14H10F2N2O5 IUPAC Name 2-[[5-(2,3-difluorophenoxy)-3-hydroxypyridine-2-carbonyl]amino]acetic acid Canonical SMILES C1=CC(=C(C(=C1)F)F)OC2=CC(=C(N=C2)C(=O)NCC(=O)O)O InChI InChI=1S/C14H10F2N2O5/c15-8-2-1-3-10(12(8)16)23-7-4-9(19)13(17-5-7)14(22)18-6-11(20)21/h1-5,19H,6H2,(H,18,22)(H,20,21) InChIKey CTRIOCMSHSAPNW-UHFFFAOYSA-N
Cross-matching ID	PubChem CID 134204791 TTD ID D0QI0J

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
HIF-prolyl hydroxylase 2 (HPH-2)	TT9ISBX	EGLN1_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

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References

1	Compound of 3-hydroxyl pyridine, preparation method thereof and pharmaceutical use thereof. US10149841.