Details of the Drug

General Information of Drug (ID: DMS8NM5)

Drug Name
OS2966
Indication
Disease Entry ICD 11 Status REF
Glioblastoma of brain 2A00.00 Phase 1 [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
DB8MR6

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Integrin beta-1 (ITGB1) TTBVIQC ITB1_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04608812) Convection-enhanced Delivery of OS2966 for Patients With High-grade Glioma Undergoing a Surgical Resection. U.S. National Institutes of Health.
2 Convection-Enhanced Delivery of a First-in-Class Anti-beta1 Integrin Antibody for the Treatment of High-Grade Glioma Utilizing Real-Time Imaging. Pharmaceutics. 2020 Dec 30;13(1):40.