Details of the Drug

General Information of Drug (ID: DMSL0Y5)

Drug Name
LOR-2501
Synonyms GTI-2501; R1 ribonucleotide reductase mRNA antisense oligo, Lorus; Antisense oligonucleotide (cancer), Lorus; U-sense technology, Lorus
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Discontinued in Phase 1 [1]
Drug Type
Antisense drug
Cross-matching ID
TTD ID
D0K4OL

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
RRM1 messenger RNA (RRM1 mRNA) TTWP0NS RIR1_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011360)
2 Non-covalent complexes of folic acid and oleic acid conjugated polyethylenimine: An efficient vehicle for antisense oligonucleotide delivery. Colloids Surf B Biointerfaces. 2015 Jul 26;135:274-282.