Details of the Drug

General Information of Drug (ID: DMST2LX)

Drug Name

2-(pyridin-2-yl)-1H-benzo[d]imidazol-5-amine

Synonyms

55396-63-9; CHEMBL199925; 2-(pyridin-2-yl)-1H-1,3-benzodiazol-5-amine; MLS000528495; 2-Pyridin-2-yl-1H-benzoimidazol-5-ylamine; 2-(pyridin-2-yl)-1H-benzo[d]imidazol-5-amine; ITFXYBZUPPBWEC-UHFFFAOYSA-N; SMR000121070; 2-pyridin-2-yl-3H-benzimidazol-5-amine; 1H-Benzimidazol-5-amine, 2-(2-pyridinyl)-; 2-(Pyridin-2-yl)-1H-1,3-benzodiazol-6-amine; AC1LBVAV; 1H-Benzimidazol-6-amine, 2-(2-pyridinyl)-; AC1Q52EP; SCHEMBL8556415; SCHEMBL4371835; cid_542828; BDBM62926; CTK1F6864; DTXSID50337459; MolPort-006-709-925; MolPort-001-815-306

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

210.23

Logarithm of the Partition Coefficient (xlogp)

1.4

Rotatable Bond Count (rotbonds)

1

Hydrogen Bond Donor Count (hbonddonor)

2

Hydrogen Bond Acceptor Count (hbondacc)

3

Chemical Identifiers

Formula: C12H10N4
IUPAC Name: 2-pyridin-2-yl-3H-benzimidazol-5-amine
Canonical SMILES: C1=CC=NC(=C1)C2=NC3=C(N2)C=C(C=C3)N
InChI: InChI=1S/C12H10N4/c13-8-4-5-9-11(7-8)16-12(15-9)10-3-1-2-6-14-10/h1-7H,13H2,(H,15,16)
InChIKey: ITFXYBZUPPBWEC-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 542828
CAS Number: 55396-63-9
TTD ID: D0L6ZY

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Methionine aminopeptidase 2 (METAP2)	TTZL0OI	MAP2_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Subtype-selectivity of metal-dependent methionine aminopeptidase inhibitors, Bioorg. Med. Chem. Lett. 20(14):4038-4044 (2010).