Details of the Drug

General Information of Drug (ID: DMTEJJT)

Drug Name

Doranidazole

Synonyms

PR-000350; PR-350; RP-343; Doranidazole; Rac-(2RS,3SR)-3-(2-Nitro-1H-imidazol-1-ylmethoxy)butane-1,2,4-triol

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Phase 3	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C8H13N3O6
Canonical SMILES: C1=CN(C(=N1)[N+](=O)[O-])COC(CO)C(CO)O
InChI: 1S/C8H13N3O6/c12-3-6(14)7(4-13)17-5-10-2-1-9-8(10)11(15)16/h1-2,6-7,12-14H,3-5H2/t6-,7+/m1/s1
InChIKey: FIITXXIVUIXYMI-RQJHMYQMSA-N

Cross-matching ID

References

1	Efficacy of novel hypoxic cell sensitiser doranidazole in the treatment of locally advanced pancreatic cancer: long-term results of a placebo-controlled randomised study. Radiother Oncol. 2008 Jun;87(3):326-30.