Details of the Drug

General Information of Drug (ID: DMTKN4A)

• Drug Name: Homoserine Lactone
• Synonyms: homoserinium lactone; 2-oxooxolan-3-aminium; homoserinium lactone(1+); homoserinium lactone cation; (2-oxooxolan-3-yl)azanium; 2-oxotetrahydrofuran-3-aminium; AC1N129K

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 101.1
  Logarithm of the Partition Coefficient (xlogp); -0.6
  Rotatable Bond Count (rotbonds); 0
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 3
• Chemical Identifiers:
  Formula: C4H7NO2
  IUPAC Name: 3-aminooxolan-2-one
  Canonical SMILES: C1COC(=O)C1N
  InChI: InChI=1S/C4H7NO2/c5-3-1-2-7-4(3)6/h3H,1-2,5H2
  InChIKey: QJPWUUJVYOJNMH-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 73509
  ChEBI ID: CHEBI:17289
  CAS Number: 1192-20-7
  DrugBank ID: DB02624
  TTD ID: D07WXS

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Sodium/hydrogen exchanger 1 (SLC9A1)	TTGSEFH	SL9A1_HUMAN	Inhibitor	[1]

References

• [1] How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.