Details of the Drug

General Information of Drug (ID: DMTT9VU)

Drug Name

Exeporfinium chloride

Synonyms

XF-73; 718638-68-7; UNII-1912L54M2V; 1912L54M2V; 3,3'-((porphyrin-5,15-diylbis(4,1-phenylene))bis(oxy))bis(N,N,N-trimethylpropan-1-aminium) chloride; Exeporfinium chloride [INN]; SCHEMBL584418; CHEMBL3822503; XF 73; Q8041945; 3,3'-(21H,23H-Porphyrin-5,15-diylbis(((4,1-phenylene)oxy)-N,N,N-trimethylpropan-1-aminium)) dichloride

Indication

Disease Entry	ICD 11	Status	REF
Staphylococcus infection	1B5Y	Phase 2	[1]
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Drug Type

Small molecular drug

Structure

3D MOL is unavailable

2D MOL

Chemical Identifiers

Formula: C44H50Cl2N6O2
Canonical SMILES: C[N+](C)(C)CCCOC1=CC=C(C=C1)C2=C3C=CC(=CC4=NC(=C(C5=CC=C(N5)C=C6C=CC2=N6)C7=CC=C(C=C7)OCCC[N+](C)(C)C)C=C4)N3.[Cl-].[Cl-]
InChI: 1S/C44H50N6O2.2ClH/c1-49(2,3)25-7-27-51-37-17-9-31(10-18-37)43-39-21-13-33(45-39)29-35-15-23-41(47-35)44(42-24-16-36(48-42)30-34-14-22-40(43)46-34)32-11-19-38(20-12-32)52-28-8-26-50(4,5)6;;/h9-24,29-30,45,48H,7-8,25-28H2,1-6H3;2*1H/q+2;;/p-2
InChIKey: KJLHJQGDBJNMPU-UHFFFAOYSA-L

Cross-matching ID

PubChem CID: 135456185
CAS Number: 718638-68-7
TTD ID: D7XNQ1

References

1	ClinicalTrials.gov (NCT03915470) Effect of Exeporfinium Chloride (XF-73) Gel on Nasal S.Aureus in Patients at Risk of Post-op Staphylococcal Infection. U.S. National Institutes of Health.