General Information of Drug (ID: DMTZC5G)

Drug Name
Bezlotoxumab
Synonyms CDB1; Clostridium difficile toxin B monoclonal antibody; MBL-CDB1; MDX-1388; MK 6072; Zinplava
Indication
Disease Entry ICD 11 Status REF
C. difficile infection 1A04 Approved [1]
Drug Type
Monoclonal antibody
ADMET Property
Clearance
The clearance of drug is 0.317 L/day []
Half-life
The concentration or amount of drug in body reduced by one-half in 19 Days [2]
Vd
The volume of distribution (Vd) of drug is 7.33 L []
Cross-matching ID
DrugBank ID
DB13140
TTD ID
D09KRE

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Clostridium difficile Toxin B (CD toxB) TTQH65V TOXB_CLODI Modulator [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 2016 FDA drug approvals. Nat Rev Drug Discov. 2017 Feb 2;16(2):73-76.
2 Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds