| Drug Name |
Levomefolic acid
|
| Synonyms |
Levomefolic acid; Levomefolinic acid; Metafolin; Metafolin (TN); L-5-Methyltetrahydrofolate; LEVOMEFOLATE; (6s)-5-methyltetrahydrofolic acid; (S)-2-(4-((((S)-2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid; 31690-09-2; 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID; 5-Methyltetrahydrofolate; 8S95DH25XC; C20H25N7O6; CHEBI:15641; LMSR; N-(5-methyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid; UNII-8S95DH25XC; [(6S)-5-methyl-5,6,7,8-tetrahydropteroyl]glutamate
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| Structure |
|
 |
|
3D MOL
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2D MOL
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| #Ro5 Violations (Lipinski): 1 |
Molecular Weight (mw) |
459.5 |
|
| Logarithm of the Partition Coefficient (xlogp) |
-0.5 |
| Rotatable Bond Count (rotbonds) |
9 |
| Hydrogen Bond Donor Count (hbonddonor) |
7 |
| Hydrogen Bond Acceptor Count (hbondacc) |
10 |
| ADMET Property |
- Absorption Cmax
-
The maximum plasma concentration (Cmax) of drug is 0.0394 micromol/L
[1]
- Half-life
-
The concentration or amount of drug in body reduced by one-half in 3 hours
[2]
- Metabolism
-
The drug is metabolized via the vitamin B12-dependent enzyme
[]
|
| Chemical Identifiers |
- Formula
- C20H25N7O6
- IUPAC Name
(2S)-2-[[4-[[(6S)-2-amino-5-methyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid - Canonical SMILES
-
CN1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
- InChI
-
ZNOVTXRBGFNYRX-STQMWFEESA-N
- InChIKey
-
1S/C20H25N7O6/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31)/t12-,13-/m0/s1
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| Cross-matching ID |
- PubChem CID
- 135398561
- ChEBI ID
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- CAS Number
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- DrugBank ID
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- INTEDE ID
- DR0940
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