Details of the Drug

General Information of Drug (ID: DMV5XR7)

• Drug Name: 6-Phenylquinazolin-4-amine
• Synonyms: CHEMBL3262570; 6-phenyl quinazolin-4-amine; SCHEMBL15587451; BDBM50011551
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 221.26
  Logarithm of the Partition Coefficient (xlogp); 2.9
  Rotatable Bond Count (rotbonds); 1
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 3
• Chemical Identifiers:
  Formula: C14H11N3
  IUPAC Name: 6-phenylquinazolin-4-amine
  Canonical SMILES: C1=CC=C(C=C1)C2=CC3=C(C=C2)N=CN=C3N
  InChI: InChI=1S/C14H11N3/c15-14-12-8-11(10-4-2-1-3-5-10)6-7-13(12)16-9-17-14/h1-9H,(H2,15,16,17)
  InChIKey: KLSNPRMSQXGJND-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 90054733
  TTD ID: D0HK8C

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
MEK kinase kinase 4 (MAP4K4)	TT6NI13	M4K4_HUMAN	Inhibitor	[1]

References

• [1] Aminoquinazoline and pyridopyrimidine derivatives. US9592235.