Details of the Drug

General Information of Drug (ID: DMVCWXD)

• Drug Name: US10022354, Example 151
• Synonyms: SCHEMBL19513974; CHEMBL4060968; BDBM281211; US10022354, Example 151
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 290.36
  Logarithm of the Partition Coefficient (xlogp); 1.1
  Rotatable Bond Count (rotbonds); 4
  Hydrogen Bond Donor Count (hbonddonor); 2
  Hydrogen Bond Acceptor Count (hbondacc); 3
• Chemical Identifiers:
  Formula: C15H22N4O2
  IUPAC Name: N-[1-(5-propan-2-yl-1H-pyrazole-3-carbonyl)pyrrolidin-3-yl]cyclopropanecarboxamide
  Canonical SMILES: CC(C)C1=CC(=NN1)C(=O)N2CCC(C2)NC(=O)C3CC3
  InChI: InChI=1S/C15H22N4O2/c1-9(2)12-7-13(18-17-12)15(21)19-6-5-11(8-19)16-14(20)10-3-4-10/h7,9-11H,3-6,8H2,1-2H3,(H,16,20)(H,17,18)
  InChIKey: CXEXTVGTDZRKJS-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 132054530
  TTD ID: D03POM

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Lysine-specific demethylase 5A (KDM5A)	TTIG67W	KDM5A_HUMAN	Inhibitor	[1]

References

• [1] IRE-1 inhibitors