Details of the Drug

General Information of Drug (ID: DMVZ9XL)

Drug Name
177Lu-labelled DOTA-JR11
Indication
Disease Entry ICD 11 Status REF
Neuroendocrine cancer 2B72.1 Phase 1/2 [1]
Drug Type
Radiopharmaceutical therapy agent
Cross-matching ID
TTD ID
DP85ES

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Somatostatin receptor (SSTR) TTOMNR9 NOUNIPROTAC Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT02592707) Study to Evaluate the Safety and Preliminary Efficacy of 177Lu-OPS201 in NETs. U.S. National Institutes of Health.
2 Multimodal Imaging of 2-Cycle PRRT with 177 Lu-DOTA-JR11 and 177 Lu-DOTATOC in an Orthotopic Neuroendocrine Xenograft Tumor Mouse Model. J Nucl Med. 2021 Mar;62(3):393-398.