Details of the Drug

General Information of Drug (ID: DMW3145)

Drug Name
ISIS 11219
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Antisense drug
Sequence
CGGGTTCTCCTGGTGGCAAT
Cross-matching ID
TTD ID
D00AJF

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Bcl-x messenger RNA (BCL2L1 mRNA) TTRE6AX B2CL1_HUMAN Not Available [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Bcl-x messenger RNA (BCL2L1 mRNA) DTT BCL2L1 7.28E-13 -0.55 -0.68
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 US patent application no. 7,148,204, Antisense modulation of bcl-x expression.