Details of the Drug

General Information of Drug (ID: DMW48JD)

Drug Name

Spiro[pyrrolidine-2,2-adamantane]

Synonyms

1'-methylspiro[adamantane-2,2'-pyrrolidine]; AC1LA6HK; CHEMBL45505; SCHEMBL17352425; SCHEMBL15922378; ZINC3639976; 1-Methylspiro[pyrrolidine-2,2'-adamantane]; Spiro[pyrrolidine-2,2'-tricyclo[3.3.1.13,7]decane], 1-methyl-

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

205.34

Logarithm of the Partition Coefficient (xlogp)

3

Rotatable Bond Count (rotbonds)

0

Hydrogen Bond Donor Count (hbonddonor)

0

Hydrogen Bond Acceptor Count (hbondacc)

1

Chemical Identifiers

Formula: C14H23N
IUPAC Name: 1'-methylspiro[adamantane-2,2'-pyrrolidine]
Canonical SMILES: CN1CCCC12C3CC4CC(C3)CC2C4
InChI: InChI=1S/C14H23N/c1-15-4-2-3-14(15)12-6-10-5-11(8-12)9-13(14)7-10/h10-13H,2-9H2,1H3
InChIKey: NEVKUUKTVIGMHH-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 508064
TTD ID: D07FOH

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Influenza M2 protein (Influ M)	TTXT3PU	M2_I34A1	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Antiviral agents active against influenza A viruses. Nat Rev Drug Discov. 2006 Dec;5(12):1015-25.