Details of the Drug

General Information of Drug (ID: DMW78BX)

Drug Name

HBX-41108

Synonyms

USP inhibitors (cancer), Hybrigenics; USP-7 inhibitors, Hybrigenics; USP-7 inhibitors (cancer), Hybrigenics; USP-9 inhibitors (cancer), Hybrigenics; Ubiquitin-specific protease inhibitors (cancer), Hybrigenics; Ubiquitin-specific protease-7 inhibitors (cancer), Hybrigenics

Indication

Disease Entry	ICD 11	Status	REF
Solid tumour/cancer	2A00-2F9Z	Preclinical	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C13H3ClN4O
Canonical SMILES: C1=CC2=C(C=C1Cl)C(=O)C3=NC(=C(N=C23)C#N)C#N
InChI: 1S/C13H3ClN4O/c14-6-1-2-7-8(3-6)13(19)12-11(7)17-9(4-15)10(5-16)18-12/h1-3H
InChIKey: BIGPXXAUSQLTQR-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 16065773
CAS Number: 924296-39-9
TTD ID: D0I9UP

References

1	Deubiquitylating enzymes and drug discovery: emerging opportunities. Nat Rev Drug Discov. 2018 Jan;17(1):57-78.