Details of the Drug

General Information of Drug (ID: DMWC4BE)

Drug Name

Cadazolid

Synonyms

1025097-10-2; ACT-179811; UNII-2OEA2UN10Y; 2OEA2UN10Y; Cadazolid [USAN:INN]; Cadazolid (USAN/INN); SCHEMBL541618; Cadazolid (ACT-179811); CHEMBL3707376; GTPL10767; DTXSID10145234; 1-Cyclopropyl-6-fluoro-7-[4-({2-fluoro-4-[(5R)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenoxy}methyl)-4-hydroxypiperidin-1-yl]-4-oxo-1,4-dihydroquinolin-3-carboxylic acid; BCP20623; EX-A1438; ACT179811; CS-6972; DB11847; SB18979; 1-Cyclopropyl-6-fluoro-7-(4-((2-fluoro-4-((R)-5-hydroxymethyl-2-oxooxazolidin-3-yl)phenoxy)methyl)-4-hydroxypiperidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; HY-100436; J3.437.086I; D11207; Q15408418; (R)-1-cyclopropyl-6-fluoro-7-(4-((2-fluoro-4-(5-(hydroxymethyl)-2-oxooxazolidin-3-yl)phenoxy)methyl)-4-hydroxypiperidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-cyclopropyl-6-fluoro-7-[4-[[2-fluoro-4-[(5R)-5-(hydroxymethyl)-2-oxo-1,3-oxazolidin-3-yl]phenoxy]methyl]-4-hydroxypiperidin-1-yl]-4-oxoquinoline-3-carboxylic acid; JJH

Indication

Disease Entry	ICD 11	Status	REF
Clostridium difficile associated diarrhea	1A04	Phase 3	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C29H29F2N3O8
Canonical SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCC(CC4)(COC5=C(C=C(C=C5)N6CC(OC6=O)CO)F)O)F)C(=O)O
InChI: 1S/C29H29F2N3O8/c30-21-10-19-23(33(16-1-2-16)13-20(26(19)36)27(37)38)11-24(21)32-7-5-29(40,6-8-32)15-41-25-4-3-17(9-22(25)31)34-12-18(14-35)42-28(34)39/h3-4,9-11,13,16,18,35,40H,1-2,5-8,12,14-15H2,(H,37,38)/t18-/m1/s1
InChIKey: XWFCFMXQTBGXQW-GOSISDBHSA-N

Cross-matching ID

PubChem CID: 44242317
CAS Number: 1025097-10-2
TTD ID: DV25QN

References

1	ClinicalTrials.gov (NCT01987895) Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile - Associated Diarrhea. U.S. National Institutes of Health.