Drug Name |
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Synonyms |
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#Ro5 Violations (Lipinski): 1 |
Molecular Weight (mw) |
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Logarithm of the Partition Coefficient (xlogp) |
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Rotatable Bond Count (rotbonds) |
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Hydrogen Bond Donor Count (hbonddonor) |
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Hydrogen Bond Acceptor Count (hbondacc) |
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ADMET Property |
- Absorption Tmax
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The time to maximum plasma concentration (Tmax) is 1.7-6.1 h
[1]
- Clearance
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The clearance of drug is 0.39-0.708 L/h/kg
[1]
- Elimination
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In radiolabeling studies, approximately 30% of the radioactivity is excreted in the urine following a single oral administration of 14C-labelled haloperidol, while 18% is excreted in the urine as haloperidol glucuronide, demonstrating that haloperidol glucuronide is a major metabolite in the urine as well as in plasma in humans
[1]
- Half-life
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The concentration or amount of drug in body reduced by one-half in 14.5 - 36.7 hours
[1]
- Metabolism
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The drug is metabolized via the liver
[1]
- Vd
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The volume of distribution (Vd) of drug is 9.5-21.7 L/kg
[1]
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Cross-matching ID |
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