Details of the Drug

General Information of Drug (ID: DMWDGCH)

• Drug Name: US10040779, Example 4
• Synonyms: SCHEMBL15792083; US10040779, Example 4; BDBM277707; 3-[(5-chloro-1-methyl-1H-indazol-3-yl)amino]pyridine-4-carboxylic acid
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 302.71
  Logarithm of the Partition Coefficient (xlogp); 3.1
  Rotatable Bond Count (rotbonds); 3
  Hydrogen Bond Donor Count (hbonddonor); 2
  Hydrogen Bond Acceptor Count (hbondacc); 5
• Chemical Identifiers:
  Formula: C14H11ClN4O2
  IUPAC Name: 3-[(5-chloro-1-methylindazol-3-yl)amino]pyridine-4-carboxylic acid
  Canonical SMILES: CN1C2=C(C=C(C=C2)Cl)C(=N1)NC3=C(C=CN=C3)C(=O)O
  InChI: InChI=1S/C14H11ClN4O2/c1-19-12-3-2-8(15)6-10(12)13(18-19)17-11-7-16-5-4-9(11)14(20)21/h2-7H,1H3,(H,17,18)(H,20,21)
  InChIKey: TXMBUJQSVXBAFZ-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 75202257
  TTD ID: D06TKT

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Lysine-specific demethylase 5A (KDM5A)	TTIG67W	KDM5A_HUMAN	Inhibitor	[1]

References

• [1] Histone demethylase inhibitors. US10040779.