Details of the Drug

General Information of Drug (ID: DMWJ0IH)

Drug Name
REGN-421
Synonyms Dll4 antibody; Dll4-Fc; Delta-like ligand 4 antibody (VelociSuite), Regeneron, sanofi-aventis
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 1 [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
D06VCC

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Delta-like protein 4 (DLL4) TTV23LH DLL4_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT00871559) A Multiple-Ascending-Dose Study of the Safety and Tolerability of REGN421(SAR153192) in Patients With Advanced Solid Malignancies. U.S. National Institutes of Health.
2 J Clin Oncol 31, 2013 (suppl; abstr 2502).