Details of the Drug | DrugMAP

General Information of Drug (ID: DMWJRY7)

Drug Name	PMID26882240-Compound-8
Drug Type	Small molecular drug
Structure
Structure	3D MOL			2D MOL
#Ro5 Violations (Lipinski): 0	Molecular Weight (mw)			286.4
	Logarithm of the Partition Coefficient (xlogp)			4.9
	Rotatable Bond Count (rotbonds)			4
	Hydrogen Bond Donor Count (hbonddonor)			1
	Hydrogen Bond Acceptor Count (hbondacc)			3
Chemical Identifiers	Formula C18H22O3 IUPAC Name 2-[4-(1-adamantyl)phenoxy]acetic acid Canonical SMILES C1C2CC3CC1CC(C2)(C3)C4=CC=C(C=C4)OCC(=O)O InChI InChI=1S/C18H22O3/c19-17(20)11-21-16-3-1-15(2-4-16)18-8-12-5-13(9-18)7-14(6-12)10-18/h1-4,12-14H,5-11H2,(H,19,20) InChIKey WIWCHWGNONICJI-UHFFFAOYSA-N
Cross-matching ID	PubChem CID 625381 CAS Number 52804-26-9 TTD ID D0V7OU

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Hypoxia-inducible factor 1 (HIF-1)	TTUX68I	NOUNIPROTAC	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2011-2015).Expert Opin Ther Pat. 2016;26(3):309-22.