Details of the Drug

General Information of Drug (ID: DMWY9GM)

• Drug Name: 1-Benzyl-3-p-tolyl-1H-pyrrole-2,5-dione
• Synonyms: CHEMBL2037371; SCHEMBL13517162; PLQCDKKQKRJJDK-UHFFFAOYSA-N; BDBM50384773; 1-benzyl-3-p-tolyl-1H-pyrrole-2,5-dione
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 277.3
  Logarithm of the Partition Coefficient (xlogp); 3
  Rotatable Bond Count (rotbonds); 3
  Hydrogen Bond Donor Count (hbonddonor); 0
  Hydrogen Bond Acceptor Count (hbondacc); 2
• Chemical Identifiers:
  Formula: C18H15NO2
  IUPAC Name: 1-benzyl-3-(4-methylphenyl)pyrrole-2,5-dione
  Canonical SMILES: CC1=CC=C(C=C1)C2=CC(=O)N(C2=O)CC3=CC=CC=C3
  InChI: InChI=1S/C18H15NO2/c1-13-7-9-15(10-8-13)16-11-17(20)19(18(16)21)12-14-5-3-2-4-6-14/h2-11H,12H2,1H3
  InChIKey: PLQCDKKQKRJJDK-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 70690209
  TTD ID: D0E9JL

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Regulator of G-protein signaling 8 (RGS8)	TTWME23	RGS8_HUMAN	Inhibitor	[1]

References

• [1] Small molecule inhibitors of RGS proteins. US8865750.