Details of the Drug

General Information of Drug (ID: DMX0GK1)

Drug Name

LYT-100

Synonyms

Deupirfenidone; LYT-100; Deupirfenidone [USAN]; 1093951-85-9; 1QC36BHI6S; SD-560; UNII-1QC36BHI6S; LYT100; 2(1H)-Pyridinone, 5-(methyl-d3)-1-phenyl-; WHO 12460; 1-Phenyl-5-(trideuteriomethyl)-1,2-dihydropyridin-2-one; Pirfenidone-D3; deupirfenidone [INN]; SCHEMBL4059454; DEUPIRFENIDONE [WHO-DD]; CHEMBL5095176; GTPL12890; GLXC-26820; HY-B0673S1; AT18410; 1-phenyl-5-(trideuteriomethyl)pyridin-2-one; 5-(methyl-d3)-1-phenylpyridin-2(1H)-one; CS-0641188

Indication

Disease Entry	ICD 11	Status	REF
Idiopathic pulmonary fibrosis	CB03.4	Phase 2	[1]
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Drug Type

Small molecule

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C12H11NO
Canonical SMILES: CC1=CN(C(=O)C=C1)C2=CC=CC=C2
InChI: InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3/i1D3
InChIKey: ISWRGOKTTBVCFA-FIBGUPNXSA-N

Cross-matching ID

PubChem CID: 25145077
TTD ID: D6BY8P

References

1	ClinicalTrials.gov (NCT05321420) A Randomized Double-blind, Four-Arm Active and Placebo-controlled Dose-Finding Trial to Evaluate the Efficacy, Tolerability, Safety and Dose Response of LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF). U.S.National Institutes of Health.