General Information of Drug (ID: DMXFLMK)

Drug Name
4-(3-cyclohexylureido)butanoic acid
Synonyms
4-{[(Cyclohexylamino)carbonyl]amino}butanoic acid; 4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID; 4-[(cyclohexylcarbamoyl)amino]butanoic acid; 511552-46-8; 4-(3-Cyclohexyl-ureido)-butyric acid; CHEMBL219695; 4-([(Cyclohexylamino)carbonyl]amino)butanoic acid; 4-(3-CYCLOHEXYLURIEDO)-BUTYRIC ACID; NC4; 1zd3; AC1O4WJY; AC1Q75I7; SCHEMBL1065092; WSVFRGGLURJIMG-UHFFFAOYSA-N; MolPort-004-290-136; HMS3604L06; ZINC8754389; BDBM50192936; AKOS000125413; 4-(3-cyclohexylur-eido)-butyric acid; NE13821; MCULE-1918218076; DB08257
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 228.29
Logarithm of the Partition Coefficient (xlogp) 1
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C11H20N2O3
IUPAC Name
4-(cyclohexylcarbamoylamino)butanoic acid
Canonical SMILES
C1CCC(CC1)NC(=O)NCCCC(=O)O
InChI
InChI=1S/C11H20N2O3/c14-10(15)7-4-8-12-11(16)13-9-5-2-1-3-6-9/h9H,1-8H2,(H,14,15)(H2,12,13,16)
InChIKey
WSVFRGGLURJIMG-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
6420119
DrugBank ID
DB08257
TTD ID
D0TS7G

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Soluble epoxide hydrolase (EPHX2) TT7WVHI HYES_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Soluble epoxide hydrolase (EPHX2) DTT EPHX2 8.78E-01 -0.1 -0.27
Soluble epoxide hydrolase (EPHX2) DTT EPHX2 4.40E-02 -0.18 -0.42
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.