Details of the Drug

General Information of Drug (ID: DMXKZDU)

Drug Name

Antova

Synonyms

Ruplizumab

Indication

Disease Entry	ICD 11	Status	REF
Thrombocytopenia	3B64	Terminated	[1]
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Cross-matching ID

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
TNF related activation protein (CD40LG)	TTIJP3Q	CD40L_HUMAN	Modulator	[2]

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Molecular Interaction Atlas (MIA)

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Molecular Expression Atlas of This Drug

The Studied Disease

Thrombocytopenia

ICD Disease Classification

3B64

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
TNF related activation protein (CD40LG)	DTT	CD40LG	8.02E-01	-0.13	-0.7

Molecular Expression Atlas (MEA)

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References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010330)
2	CD40 and Autoimmunity: The Dark Side of a Great Activator