Details of the Drug

General Information of Drug (ID: DMY2MO4)

• Drug Name: Anti-meso-CAR T cells

Indication

Disease Entry	ICD 11	Status	REF
Mesothelin Positive tumour	2C51-2F10	Phase 1	[1]

• Drug Type: CAR T Cell Therapy
• Cross-matching ID: TTD ID: D0CA3M

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Mesothelin (MSLN)	TT4RXME	MSLN_HUMAN	CAR-T-Cell-Therapy	[1]

Molecular Expression Atlas of This Drug

• The Studied Disease: Mesothelin Positive tumour
• ICD Disease Classification: 2C51-2F10

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Mesothelin (MSLN)	DTT	MSLN	2.86E-20	3.98	6.12

References

• [1] ClinicalTrials.gov (NCT02580747) Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART-meso