General Information of Drug (ID: DMZD7OA)

Drug Name
Quaratusugene ozeplasmid
Synonyms GPX-001; CNVN 202
Indication
Disease Entry ICD 11 Status REF
Non-small-cell lung cancer 2C25.Y Phase 1/2 [1]
Drug Type
Gene therapy
Cross-matching ID
TTD ID
DVD0E9

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tumor suppressor candidate 2 (TUSC2) TTJ8O14 TUSC2_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Non-small-cell lung cancer
ICD Disease Classification 2C25.Y
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Tumor suppressor candidate 2 (TUSC2) DTT TUSC2 3.62E-08 -0.16 -0.72
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04486833) TUSC2-nanoparticles (GPX-001) and Osimertinib in Patients With Stage IV Lung Cancer Who Progressed on Osimertinib Alone. U.S. National Institutes of Health.
2 Clinical pipeline report, company report or official report of Genprex.