Details of the Drug

General Information of Drug (ID: DMZG90L)

Drug Name

CS-461

Synonyms

CS-461; CS 461; Thiazolium, 3-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-en-3-yl)methyl)-5-(2-hydroxyethyl)-4-methyl-, (6R-(6alpha,7beta(Z)))-, sulfate (1:1) (salt); Thiazolium, 3-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-5-(2-hydroxyethyl)-4-methyl-, (6R-(6-alpha,7-beta(Z)))-, sulfate (1:1) (salt); 115948-58-8; 134102-27-5; LS-151924

Indication

Disease Entry	ICD 11	Status	REF
Bacterial infection	1A00-1C4Z	Terminated	[1]
------------------------------------------------------------------------------------

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C20H24N6O10S4
Canonical SMILES: CC1=C(SC=[N+]1CC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O)CCO.OS(=O)(=O)[O-]
InChI: 1S/C20H22N6O6S3.H2O4S/c1-9-12(3-4-27)35-8-25(9)5-10-6-33-18-14(17(29)26(18)15(10)19(30)31)23-16(28)13(24-32-2)11-7-34-20(21)22-11;1-5(2,3)4/h7-8,14,18,27H,3-6H2,1-2H3,(H3-,21,22,23,28,30,31);(H2,1,2,3,4)/b24-13+;/t14-,18-;/m1./s1
InChIKey: WNNXOUAREUXOEN-CZFAVYDOSA-N

Cross-matching ID

PubChem CID: 9577436
CAS Number: 115948-58-8
TTD ID: D00SIR

References

1	Cephalosporin antibiotics. II. Synthesis and biological properties of CS-461 and related compounds. J Antibiot (Tokyo). 1991 Aug;44(8):864-9.