Details of the Drug

General Information of Drug (ID: DMZUM67)

• Drug Name: M9241
• Synonyms: NHS-IL12

Indication

Disease Entry	ICD 11	Status	REF
Pancreatic cancer	2C10	Phase 1	[1]

• Cross-matching ID: TTD ID: DO8W9E

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Interleukine 12 (IL-12)	TTG68FB	IL12A_HUMAN ; IL12B_HUMAN	Replacement	[2]

References

• [1] ClinicalTrials.gov (NCT04327986) Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Advanced Pancreas Cancer. U.S. National Institutes of Health.
• [2] Clinical pipeline report, company report or official report of EMD Serono.