| DTP Name |
Putative sodium-coupled neutral amino acid transporter 8 (SLC38A8)
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| Gene Name |
SLC38A8
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| UniProt ID |
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| VARIDT ID |
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| 3D Structure |
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| Synonyms |
FVH2; SLC38A8; Solute carrier family 38 member 8 |
| DTP Family |
Amino Acid/Auxin Permease (AAAP) Family
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| Tissue Specificity |
Expressed in fetal and adult brain, and spinalcord. In the brain, it is localized in the cell body and axon ofthe majority of neuronal cells and in a subset of glial cells.Found throughout the neuronal retina, with higher expressionlevels in the inner and outer plexiform layers and thephotoreceptor layer. Very weak expression is also present in thekidneys, thymus, and testes.
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| Sequence |
MEGQTPGSRGLPEKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFL
VELVSLVFLISGLVILGYAAAVSGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFL
RVIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILG
TLAACYLALVITVQYYLWPQGLVRESHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIYC
SMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARV
LFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLA
MALFMPDLSEIVSIIGGISSFFIFIFPGLCLICAMGVEPIGPRVKCCLEVWGVVSVLVGT
FIFGQSTAAAVWEMF
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| Function |
This transporter is putative sodium-dependent amino acid/proton antiporter. |
| Endogenous Substrate(s) |
Amino acids; Proton
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| TCDB ID |
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| Gene ID |
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