Details of the Drug Transporter (DTP)

General Information of Drug Transporter (DTP) (ID: DTGQ2CF)

• DTP Name: Annexin A11 (ANXA11)
• Gene Name: ANXA11
• UniProt ID: P50995 (ANX11_HUMAN)
• VARIDT ID: DTD0514
• Synonyms: 56 kDa autoantigen; ALS23; ANX11; ANXA11; Annexin XI; Annexin-11; CAP-50; CAP50; Calcyclin-associated annexin 50
• DTP Family: General Secretory Pathway (SEC) Family
• Sequence:
  MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAAN
  MSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY
  PPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT
  PAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILL
  SFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILA
  SRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRD
  AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE
  GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS
  LYHDISGDTSGDYRKILLKICGGND
• Function: This transporter binds specifically to calcyclin in a calcium-dependent manner. Required for midbody formation and completion of the terminal phase of cytokinesis.
• Endogenous Substrate(s): Proteins
• TCDB ID: 3.A.5.9.1
• Gene ID: 311
• KEGG Pathway: Amyotrophic lateral sclerosis (hsa05014)